DAMPs/PAMPs Induce Neuroinflammation

This template shows how damage- and pathogen-associated molecular patterns (DAMPs/PAMPs) in a specific brain region drive polarization of M0 macrophages into pro-inflammatory M1 cells, marked by increased TNF-alpha, iNOS, IL-1beta, IL-6, IL-12, and IL-23, versus anti-inflammatory M2 cells marked by increased Arg-1, TGF-beta, and IL-10. A seesaw icon shows the balance tipping toward a pro-inflammatory response.

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