The Diversity Outbred (DO) Mice

Eight mouse strains that capture much of the genetic diversity of all inbred mouse strains were chosen to develop an outbred population suitable for genetic association studies, the Diversity Outbred (DO) mice. Five of the strains are widely used and known to have specific phenotypes; NOD mice develop autoimmune diabetes, NZO mice develop obesity and type 2 diabetes, C57BL/6J mice are susceptible to diet-induced obesity and metabolic syndrome. A/J mice are relatively resistant to diet-induced metabolic disease. Three wild-derived strains, CAST, PWK, and WSB, contribute much of the genetic diversity of this population and often have alleles with phenotype values quite distinct from those of the other strains.

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

Yes, BioRender icons and templates meet journal, grant, and copyright standards for publication, and many researchers cite BioRender directly in their figure legends.

Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.