Biogenesis and Functions of CircRNAs

This template outlines five roles of circular RNAs, showing how RNA polymerase II transcription with U1 snRNP and back-splicing of pre-mRNA exons produces exon-intron, exonic, and intronic circRNAs. It then illustrates these circRNAs acting as miRNA sponges, RBP sponges, translation templates, and TET1 protein recruiters.

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