Extracellular Matrix-Based Strategy for Intervertebral Disc Regeneration

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. Intervertebral disc (IVD) is harvested from human spine and native cells removed through an optimized decellularization protocol. The newly formed extracellular matrix (ECM)-based scaffold is combined with mesenchymal stem/stromal cells (MSCs) collected from patients. The scaffold is then processed to form an ECM-based hydrogel which can be injected in the tissue as a minimally invasive strategy for IVD repair/regeneration.

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