IgA Transport Across Type I Epithelia

This template shows four steps of IgA transport across type I epithelia, starting with IgA dimer binding to the polymeric immunoglobulin receptor on the basolateral face of an epithelial cell. The complex undergoes endocytosis and transcytosis to the apical face, where the IgA dimer is released along with a secretory component into the gut lumen.

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