SARS-CoV-2: What We Know About Its Effects on Respiration

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. After entering the body through the mouth or nose, SARS-CoV-2 makes its way into the the lungs, where it uses its distinctive spike proteins to infect alveolar cells. In response, the immune system attacks the area of infection, killing healthy alveolar cells in the process. Reduced surfactant from alveolar epithelial type II cells, along with increased fluid accumulation in the alveoli causes reduced or severely hindered gas exchange.

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