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Huntington's Disease Molecular Mechanisms and Therapies

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Martina Maritan

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Description: This template traces Huntington's disease molecular mechanisms from the CAG-repeat-expanded huntingtin gene through mHtt protein misfolding, transcription dysregulation, mitochondrial dysfunction, and formation of intranuclear and cytoplasmic aggregates and inclusions. It also marks candidate therapies, including siRNA, BDNF mimetics, HDAC inhibitors, protease inhibitors, antioxidants, and autophagy activators, at each step they target.

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What does the Huntington's Disease Molecular Mechanisms and Therapies template show?

This template traces Huntington's disease molecular mechanisms from the CAG-repeat-expanded huntingtin gene through mHtt protein misfolding, transcription dysregulation, mitochondrial dysfunction, and formation of intranuclear and cytoplasmic aggregates and inclusions. It also marks candidate therapies, including siRNA, BDNF mimetics, HDAC inhibitors, protease inhibitors, antioxidants, and autophagy activators, at each step they target.

Is the Huntington's Disease Molecular Mechanisms and Therapies template free to use?

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Can I edit or customize this template?

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

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Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

What is Huntington's Disease Molecular Mechanisms and Therapies used for / who typically uses this template?

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.