Modèle BioRender

Application of Falcon Technology to Charcot-Marie-Tooth disease type 1A (CMT1A)

Créé par

Gaia Lugano

•

BioRender Team

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Description: This template compares healthy nerves, CMT1A-affected nerves, and Falcon PIMP22 siRNA treated nerves in Charcot-Marie-Tooth disease type 1A. It shows how three copies of the PIMP22 gene cause PIMP overexpression in Schwann cells and destabilized myelin with inefficient signal transmission, while Falcon siRNA removes the extra gene copy to restore normal expression and improved signal transmission.

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What does the Application of Falcon Technology to Charcot-Marie-Tooth disease type 1A (CMT1A) template show?

This template compares healthy nerves, CMT1A-affected nerves, and Falcon PIMP22 siRNA treated nerves in Charcot-Marie-Tooth disease type 1A. It shows how three copies of the PIMP22 gene cause PIMP overexpression in Schwann cells and destabilized myelin with inefficient signal transmission, while Falcon siRNA removes the extra gene copy to restore normal expression and improved signal transmission.

Is the Application of Falcon Technology to Charcot-Marie-Tooth disease type 1A (CMT1A) template free to use?

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