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Membrane Atg8ylation & Ubiquitin Comparison

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Vojo Deretic, PhD

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Description: Membrane atg8ylation is covalent membrane modification by ubiquitin-like proteins of the mammalian ATG8 family (mATG8s), which includes LC3A, LC3B, LC3B2, LC3C, GABARAP, GABARAPL1, and GABARAPL2. It is a response to membrane stress, damage, and remodeling signals and participates in various atg8ylation-dependent processes, including canonical autophagy and a range of non-autophagic phenomena. Adapted from Figure 1 of the article 'Membrane atg8ylation in Canonical and Noncanonical Autophagy'.

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What does the Membrane Atg8ylation & Ubiquitin Comparison template show?

Membrane atg8ylation is covalent membrane modification by ubiquitin-like proteins of the mammalian ATG8 family (mATG8s), which includes LC3A, LC3B, LC3B2, LC3C, GABARAP, GABARAPL1, and GABARAPL2. It is a response to membrane stress, damage, and remodeling signals and participates in various atg8ylation-dependent processes, including canonical autophagy and a range of non-autophagic phenomena. Adapted from Figure 1 of the article 'Membrane atg8ylation in Canonical and Noncanonical Autophagy'.

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