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CRISPR Technology: Epigenome Editing

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Samara Ona
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Description: This template shows CRISPR-based epigenome editing using a dCas9 fusion protein with an effector domain that is guided to a specific DNA sequence near existing epigenetic modifications on nucleosomes. Before editing, the modifications keep the downstream locus repressed, while after epigenetic editing by the dCas9-effector complex, the modifications are removed and the locus becomes activated.

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What does the CRISPR Technology: Epigenome Editing template show?

This template shows CRISPR-based epigenome editing using a dCas9 fusion protein with an effector domain that is guided to a specific DNA sequence near existing epigenetic modifications on nucleosomes. Before editing, the modifications keep the downstream locus repressed, while after epigenetic editing by the dCas9-effector complex, the modifications are removed and the locus becomes activated.

Is the CRISPR Technology: Epigenome Editing template free to use?

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Can I edit or customize this template?

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

Is this template accepted for use in journals, theses, or grant applications?

Yes, BioRender icons and templates meet journal, grant, and copyright standards for publication, and many researchers cite BioRender directly in their figure legends.

How do I cite BioRender if I use this template?

Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

What is CRISPR Technology: Epigenome Editing used for / who typically uses this template?

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.

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