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Mechanism of Allergic Inflammation Induction

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Eunice Huang

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Description: This template shows how an allergen crossing disrupted epithelium is captured by a dendritic cell and presented to a naive T cell, which differentiates into a Th2 cell and interacts with a B cell through CD28/CD80/86 and CD40/CD40L signaling to drive IgE production. The resulting allergen-specific IgE binds mast cells, triggering mediator release and allergic reactions.

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What does the Mechanism of Allergic Inflammation Induction template show?

This template shows how an allergen crossing disrupted epithelium is captured by a dendritic cell and presented to a naive T cell, which differentiates into a Th2 cell and interacts with a B cell through CD28/CD80/86 and CD40/CD40L signaling to drive IgE production. The resulting allergen-specific IgE binds mast cells, triggering mediator release and allergic reactions.

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