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miRNA Activity Suppression with miRNA Sponges

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Description: This template compares gene silencing with and without a miRNA sponge, showing that without a sponge, miRNA loads onto the AGO-containing RISC complex and binds target mRNA to cause translational repression and mRNA degradation. When a miRNA sponge is present, it sequesters the miRNA and prevents RISC complex formation, relieving translational repression of the target mRNA.

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What does the miRNA Activity Suppression with miRNA Sponges template show?

This template compares gene silencing with and without a miRNA sponge, showing that without a sponge, miRNA loads onto the AGO-containing RISC complex and binds target mRNA to cause translational repression and mRNA degradation. When a miRNA sponge is present, it sequesters the miRNA and prevents RISC complex formation, relieving translational repression of the target mRNA.

Is the miRNA Activity Suppression with miRNA Sponges template free to use?

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Can I edit or customize this template?

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

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Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

What is miRNA Activity Suppression with miRNA Sponges used for / who typically uses this template?

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.

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