Modèle BioRender

Activation of NF-kB/MAPK Intracellular Pathways in Psoriasis

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Créé par 
Gaia Lugano
  •  
BioRender Team
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Description: This template shows how IL-1, IL-36, TNF-alpha, and IL-17 receptor signaling converge through adaptor complexes like MyD88/TRAF6, TRADD/TRAF2/RIPK1, and CARD14/TRAF6/ACT1 to activate TAK1, leading to phosphorylation of JNK, ERK, and P38 as well as IkBalpha degradation and NF-kB nuclear translocation. Both the MAPK/AP1 branch and the NF-kB/C-EBPs branch drive transcription of antimicrobial peptides and chemokines including Cxcl1/2/8 and Ccl20 in psoriasis.

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What does the Activation of NF-kB/MAPK Intracellular Pathways in Psoriasis template show?

This template shows how IL-1, IL-36, TNF-alpha, and IL-17 receptor signaling converge through adaptor complexes like MyD88/TRAF6, TRADD/TRAF2/RIPK1, and CARD14/TRAF6/ACT1 to activate TAK1, leading to phosphorylation of JNK, ERK, and P38 as well as IkBalpha degradation and NF-kB nuclear translocation. Both the MAPK/AP1 branch and the NF-kB/C-EBPs branch drive transcription of antimicrobial peptides and chemokines including Cxcl1/2/8 and Ccl20 in psoriasis.

Is the Activation of NF-kB/MAPK Intracellular Pathways in Psoriasis template free to use?

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

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Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

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Yes, BioRender icons and templates meet journal, grant, and copyright standards for publication, and many researchers cite BioRender directly in their figure legends.

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Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

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Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.

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