Modèle BioRender

Adrenergic Stimulation in Smooth Muscle Cells

Créé par

Sally Kim

•

BioRender Team

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Description: This template shows how norepinephrine binds the alpha-1 adrenergic receptor on a smooth muscle cell, activating a G-protein and phospholipase C to produce DAG and IP3 from PIP2. IP3 triggers calcium release from the endoplasmic reticulum while DAG activates PKC, and both pathways converge to cause phosphorylation of targets and contraction of the smooth muscle.

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What does the Adrenergic Stimulation in Smooth Muscle Cells template show?

This template shows how norepinephrine binds the alpha-1 adrenergic receptor on a smooth muscle cell, activating a G-protein and phospholipase C to produce DAG and IP3 from PIP2. IP3 triggers calcium release from the endoplasmic reticulum while DAG activates PKC, and both pathways converge to cause phosphorylation of targets and contraction of the smooth muscle.

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