Modèle BioRender

Canonical OxPhos Model for Insulin Secretion

Créé par

Sophia Dewing

•

BioRender Team

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Description: This template shows the canonical oxidative phosphorylation (OxPhos) model for insulin secretion, in which glucose entering through GLUT transporters fuels oxidative phosphorylation in the mitochondrion, raising the cytosolic ATP/ADP ratio. This closes K-ATP channels and opens Ca2+ channels, triggering glucose-stimulated insulin secretion.

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What does the Canonical OxPhos Model for Insulin Secretion template show?

This template shows the canonical oxidative phosphorylation (OxPhos) model for insulin secretion, in which glucose entering through GLUT transporters fuels oxidative phosphorylation in the mitochondrion, raising the cytosolic ATP/ADP ratio. This closes K-ATP channels and opens Ca2+ channels, triggering glucose-stimulated insulin secretion.

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