Modèle BioRender

Epigenetic Deregulation in Cancer

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Description: This template shows three mechanisms of epigenetic deregulation in cancer: chromatin remodeling, where loss of H4K20me3 and gain of H4K16Ac through HAT and KDM6/4 activity increases transcription at enhancers and promoters, and DNA methylation, where reduced SAM leads to loss of methyl groups and aberrant gene transcription. It also shows non-coding RNA regulation, where lncRNA affects PolII-driven transcription and miRNA loss alters mRNA stability and translation of oncogenic gene targets.

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What does the Epigenetic Deregulation in Cancer template show?

This template shows three mechanisms of epigenetic deregulation in cancer: chromatin remodeling, where loss of H4K20me3 and gain of H4K16Ac through HAT and KDM6/4 activity increases transcription at enhancers and promoters, and DNA methylation, where reduced SAM leads to loss of methyl groups and aberrant gene transcription. It also shows non-coding RNA regulation, where lncRNA affects PolII-driven transcription and miRNA loss alters mRNA stability and translation of oncogenic gene targets.

Is the Epigenetic Deregulation in Cancer template free to use?

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

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Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

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