Common Mechanisms Resulting in Uniparental Disomy (UPD)

This template compares three mechanisms producing uniparental disomy, showing maternal nondisjunction in meiosis I leading to trisomy rescue with loss of one homologue, monosomy rescue with duplication, and postzygotic mitotic crossing over. Each pathway is illustrated with colored chromosome icons showing how the resulting conceptus becomes biparental, maternal heterodisomy, paternal isodisomy, or segmental uniparental disomy.

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

Yes, BioRender icons and templates meet journal, grant, and copyright standards for publication, and many researchers cite BioRender directly in their figure legends.

Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.