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BioRender Template
Common Mechanisms Resulting in Uniparental Disomy (UPD)
Description
This template compares three mechanisms producing uniparental disomy, showing maternal nondisjunction in meiosis I leading to trisomy rescue with loss of one homologue, monosomy rescue with duplication, and postzygotic mitotic crossing over. Each pathway is illustrated with colored chromosome icons showing how the resulting conceptus becomes biparental, maternal heterodisomy, paternal isodisomy, or segmental uniparental disomy.
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