Modèle BioRender

Common Mechanisms Resulting in Uniparental Disomy (UPD)

Créé par

Nick Delrose

•

BioRender Team

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Description: This template compares three mechanisms producing uniparental disomy, showing maternal nondisjunction in meiosis I leading to trisomy rescue with loss of one homologue, monosomy rescue with duplication, and postzygotic mitotic crossing over. Each pathway is illustrated with colored chromosome icons showing how the resulting conceptus becomes biparental, maternal heterodisomy, paternal isodisomy, or segmental uniparental disomy.

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What does the Common Mechanisms Resulting in Uniparental Disomy (UPD) template show?

This template compares three mechanisms producing uniparental disomy, showing maternal nondisjunction in meiosis I leading to trisomy rescue with loss of one homologue, monosomy rescue with duplication, and postzygotic mitotic crossing over. Each pathway is illustrated with colored chromosome icons showing how the resulting conceptus becomes biparental, maternal heterodisomy, paternal isodisomy, or segmental uniparental disomy.

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