Modèle BioRender

Biliary Tract Cancers Molecular Cascades

Créé par

Samara Ona

•

BioRender Team

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Description: This template shows five receptor tyrosine kinases (FGFR2, HER2, EGFR, VEGFR, ROS) at the cell membrane converging on the PI3K/Akt/mTORC1 and RAS/Raf/MEK/ERK signaling cascades in biliary tract cancer cells. It also traces the citrate to alpha-ketoglutarate pathway in the cytoplasm and mitochondria, showing how IDH1 and IDH2 mutations produce D-2HG, which along with the kinase pathways can lead to BAP1 mutations and other DNA damage response deficiencies.

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What does the Biliary Tract Cancers Molecular Cascades template show?

This template shows five receptor tyrosine kinases (FGFR2, HER2, EGFR, VEGFR, ROS) at the cell membrane converging on the PI3K/Akt/mTORC1 and RAS/Raf/MEK/ERK signaling cascades in biliary tract cancer cells. It also traces the citrate to alpha-ketoglutarate pathway in the cytoplasm and mitochondria, showing how IDH1 and IDH2 mutations produce D-2HG, which along with the kinase pathways can lead to BAP1 mutations and other DNA damage response deficiencies.

Is the Biliary Tract Cancers Molecular Cascades template free to use?

Yes, you can customize this template with a free BioRender account (no credit card required). Paid plans unlock additional export formats, higher-resolution downloads, and publication permissions.

Can I edit or customize this template?

Yes, every element is fully editable. Icons, labels, colors, arrows, shapes and layout can all be changed to match your preferences or needs using BioRender's drag-and-drop editor. You can add or remove elements to fully customize your use case.

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Yes, BioRender icons and templates meet journal, grant, and copyright standards for publication, and many researchers cite BioRender directly in their figure legends.

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Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

What is Biliary Tract Cancers Molecular Cascades used for / who typically uses this template?

Researchers and scientists use this template for publications, funding proposals, grant applications, presentations, posters, and more.