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BioRender Template
Activation of T-cells
Creator
s
Description
Three signals are required for the activation of T-cells. The first signal is comprised of the recognition of the peptide-MHC complex by the T-cell receptor (TCR). The second signal is the interaction between the CD28 molecule present on the surface of the T-cell and the B7 molecule expressed by the antigen-presenting cell (APC). The third signal is the costimulatory cytokine secreted by the APC, which binds to the cytokine receptor present on the surface of the T-cell.
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