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Effect of cadmium on RPE cells in retina
Description
Effect of cadmium (Cd) on retinal pigment epithelium (RPE) cells. It is hypothesized that Cd enters cells via the divalent metal transporter 1 (DMT1) and voltage-gated calcium channel (VGCC). Exposure to Cd increases the production of reactive oxygen species (ROS). ROS is responsible for autophagy and endoplasmic reticulum (ER) stress.
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