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Effects on excitatory/inhibitory ratio and inflammasome NLRP3 activation after 6-OHDA lesion
Creator
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Description
In a mouse model of ADHD, 6-OHDA lesion alters the excitatory/inhibitory relationship and dopamine deficiency activates the NLRP3 inflammasome. As a result, characteristic symptoms of ADHD occur that depend on neuroinflammation. Suggesting that targetinc neuroinflammation could be a new therapeutic target for ADHD.
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