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BioRender Template
Pre-Eclampsia Prevents Mother-to-Child HIV Transmission
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Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
Placental anti-histone 2A (H2A) staining reveals a protective role of pre-eclampsia on mother-to-child transmission of HIV. In normotensive placentae, H2A+ (receptor-expressing) syncytiotrophoblasts (STB) allow the transmission of HIV from the maternal to fetal circulation. The pathologies linked to pre-eclampsia such as syncytial bridges (SB) promote the localization of H2A- (receptor-less) STB on the periphery, forming a barrier against mother-to-child transmission of HIV.
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