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PTEN Loss Confers Resistance to Anti–PD-1 Therapy in NSCLC by Increasing Tumor Infiltration of Tregs

An editable high resolution scientific image depicting PTEN Loss Confers Resistance to Anti–PD-1 Therapy in NSCLC by Increasing Tumor Infiltration of Tregs

Description

PTEN loss in NSCLC makes the tumor refractory to anti–PD-1, highly metastatic and fibrotic, and secrets TGFβ/CXCL10 to promote conversion of CD4+ lymphocytes into regulatory T cells (Tregs)
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