Figure 4. cGAS is activated by mtDNA, thereby catalyzing the formation of cGAMP. cGAMP binds to STING and promotes its transfer from the endoplasmic reticulum to the Golgi apparatus, subsequently activating downstream inflammatory pathways.
Created in BioRender. Deng, C. (2025) https://app.biorender.com/citation/682aed01e264e6c34594915f
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Deng, C. (2025). Figure 4. cGAS is activated by mtDNA, thereby catalyzing the formation of cGAMP. cGAMP binds to STING and promotes its transfer from the endoplasmic reticulum to the Golgi apparatus, subsequently activating downstream inflammatory pathways.. Created in BioRender. https://app.biorender.com/citation/682aed01e264e6c34594915f