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2021 Nobel Prize in Physiology or Medicine: Temperature Perception
Description
This template explains the 2021 Nobel Prize in Physiology or Medicine awarded to David Julius for research on temperature perception, showing a row of TRP ion channels including TRPM8, TRPM2, TRPV1, TRPA1, and TRPM3 that activate across a cold to hot temperature range. It also shows a three-step nociception pathway in which heat activates TRPV1 channels in the skin, the signal travels through spinal nerves, and the brain generates a pain response, along with potential applications for pain therapy and biosensors.
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