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Action of Antiepileptic Drugs on Inhibitory Synapses
Description
This template shows how antiepileptic drugs act on an inhibitory synapse, tracing glutamate conversion to GABA, its vesicular release, and its clearance by the GAT1 transporter or breakdown via GABA-T. It marks where vigabatrin blocks GABA-T, tiagabine blocks GAT1 reuptake, and drugs such as benzodiazepines, barbiturates, felbamate, topiramate, and zonisamide act on the postsynaptic GABA-A receptor.
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