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Acute-Phase Proteins
Description
This template shows how bacteria induce macrophages to produce IL-6, which acts on the liver to generate acute-phase proteins including serum amyloid protein, C-reactive protein, fibrinogen, mannose-binding lectin, and surfactant proteins SP-A and SP-D. Below, two panels show C-reactive protein and mannose-binding lectin binding bacterial surfaces to act as opsonins that promote phagocytosis and complement activation.
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