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BioRender Template
AGEs formation pathways (Diabetes Mellitus)
Creator
s
Description
AGEs are produced because of glycolysis and many other pathways, which is a major contributor to the diabetic state. When AGEs and RAGE interact, numerous pathways, including JNK, NFkB, AMPK, PI3K Akt, PPARγ, and others, are activated, which causes oxidative stress and inflammation. Consequently, AGE/RAGE signaling interventions aid in the management of diabetes.
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