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Antibodies that React with Endothelium Cause Hyperacute Graft Rejection
Description
This template shows a three-step sequence of hyperacute graft rejection, starting with a normal kidney grafted into a patient with a defective kidney, followed by a cross-section of the graft blood vessel where pre-existing host antibodies bind donor vascular endothelium and trigger an inflammatory response. The final panel shows the graft becoming engorged, purple, and dead due to hemorrhage and vessel occlusion.
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