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Antibody-Drug Conjugate Mechanism of Action
Description
This template shows the mechanism of action of an antibody-drug conjugate, illustrating targeted drug delivery into a cancer cell where the conjugate is internalized and releases its cytotoxic payload, pro-survival receptor blockade by the antibody portion, and antibody-dependent cellular cytotoxicity mediated by an effector cell. These combined actions lead to apoptosis of the cancer cell, shown as a fragmented cell on the right.
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