BioRender Template

Antigen-specific vs. Bystander T Cell Activation

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Catherine C

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BioRender Team

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Description: This template compares two modes of T cell activation, with antigen-specific activation on the left showing a dendritic cell presenting antigen via MHC II and TCR alongside CD28/B7 costimulation and cytokine signals. Bystander activation is shown on the right, where bacteria trigger TLR2 and TLR4 receptors on the T cell to release cytokines without direct antigen recognition.

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What does the Antigen-specific vs. Bystander T Cell Activation template show?

This template compares two modes of T cell activation, with antigen-specific activation on the left showing a dendritic cell presenting antigen via MHC II and TCR alongside CD28/B7 costimulation and cytokine signals. Bystander activation is shown on the right, where bacteria trigger TLR2 and TLR4 receptors on the T cell to release cytokines without direct antigen recognition.

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