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Apical Periodontitis Immunology
Description
Cellular components and mediators play crucial roles in the inflammation and bone metabolism associated with apical periodontitis. Cytokines like IL-1β, IL-1α, IL-6, TNF-α, and INF-γ regulates inflammation, while RANK, RANKL, and OPG are pivotal for bone metabolism regulation in this condition. IL, Interleukin; TNF, Tumor necrosis factor; INF, Interferon; RANK, Receptor Activator of Nuclear Factor κB; RANKL, Receptor Activator of Nuclear Factor κB Ligand; OPG, Osteoprotegerin.
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