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BioRender Template
Apoptosis pathway
Description
This template maps the extrinsic and intrinsic apoptosis pathways, showing death receptor and adapter protein activation of procaspase 8/10 on one side, and DNA damage triggering p53, BAX, BAK, NOXA, and PUMA in the nucleus on the other. Both pathways converge through mitochondrial cytochrome c release, apoptosome formation with Apaf-1, and activation of caspases 3, 6, and 7, culminating in apoptosis.
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