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BioRender Template
Atopic Dermatitis: Therapeutic Molecules Inhibiting Janus Kinases (JAK)
Description
This template shows how the receptors for IL-4, IL-13, IL-5, and IL-22 in atopic dermatitis skin cells signal through paired JAK proteins, which can be blocked by JAK inhibitors grouped by selectivity. Categories shown include pan-JAK inhibitors like delgocitinib and jaktinib, JAK1 inhibitors like upadacitinib and abrocitinib, JAK1/JAK2 inhibitors like baricitinib and ruxolitinib, and JAK1/JAK3 and JAK1/TYK2 inhibitors.
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