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Atopic Dermatitis: Therapeutic Molecules Targeting Pruritus
Description
This template shows therapeutic molecules targeting pruritus in atopic dermatitis by acting on NK1R, IL-31R, and P2X3 receptors on sensory nerve endings in the skin. Serlopitant and tradipitant block NK1R, nemolizumab and vixarelimab block IL-31R, and BLU-5937 blocks P2X3 to reduce itch signaling from the affected epidermis.
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