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Avery, MacLeod and McCarty’s Experiment (1944)
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Description
What kind of molecule from within the S-type cells was responsible for the transformation? To answer this, researchers named Avery, MacLeod and McCarty separated the S-type cells into various components, such as proteins, polysaccharides, lipids, and nucleic acids. Only the nucleic acids from S-type cells were able to make the R-strains smooth and fatal. Furthermore, when cellular extracts of S-type cells were treated with DNase (an enzyme that digests DNA), the transformation ability was lost.
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