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Bioengineered vascular grafts with a pathogenic TGFBR1 variant model aneurysm formation

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Ying Yang

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Description: Schematic illustration of bioengineered vessel grafts generation using human induced pluripotent stem cells-derived SMCs through CPC lineage. TGFBR1+/+ and TGFBR1A230T/+ M-SMCs were seeded onto biodegradable PGA-based mesh and cultured for 8 weeks in vitro.

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What does the Bioengineered vascular grafts with a pathogenic TGFBR1 variant model aneurysm formation template show?

Schematic illustration of bioengineered vessel grafts generation using human induced pluripotent stem cells-derived SMCs through CPC lineage. TGFBR1+/+ and TGFBR1A230T/+ M-SMCs were seeded onto biodegradable PGA-based mesh and cultured for 8 weeks in vitro.

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