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BioRender Template

Blockade of CTLA-4 or PD-1 Signaling in Tumor Immunotherapy

Akiko Iwasaki
3+
Akiko Iwasaki
,
BioRender Team
Creator
s
An editable high resolution scientific image depicting Blockade of CTLA-4 or PD-1 Signaling in Tumor Immunotherapy

Description

This template shows how blockade of CTLA-4 or PD-1 signaling enhances tumor immunotherapy across the priming phase in the lymph node and the effector phase in peripheral tissue. Insets show dendritic cells activating naive T cells via MHC-TCR and B7-CD28 interactions with CTLA-4 blocked, and activated T cells attacking tumor cells via TCR-MHC interactions with PD-1/PD-L1 signaling blocked.

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