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Calcium Pathways in Smooth Muscle Cells
Description
Calcium enters the SMC after a change in membrane potential, via transmembrane voltage-gated calcium channels (T-Type Channels & L-Type Channels), intracellular stores, and / or intercellular gap junctions. This influx drives the contraction of smooth muscle.
Sarcoplasmic Reticulum (SR)
Ryanodine Receptor (RyRe).
Calmodulin (CaM)
Myosin Light-Chain Kinase (MLCK)
Phosphorylated Myosin Light Chain (MLC+P)
Sarco / Endoplasmic Reticulum Calcium ATPase (SERCA) Pump
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