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BioRender Template
cAMP Signaling and the Role of Hydrogen Sulfide in Testosterone Synthesis
Creator
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Description
This figure illustrates the regulation of testosterone synthesis through the cAMP signaling pathway. Panel A shows normal activation of protein kinase A (PKA) and transcription factors leading to testosterone production. Panel B demonstrates pathway inhibition due to cAMP degradation by PDE. Panel C highlights the role of hydrogen sulfide (H₂S) via persulfidation in inhibiting PDE, restoring cAMP levels, and promoting testosterone synthesis.
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