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BioRender Template
Cancer development and progression
Creator
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Description
The accumulation of genetic and epigenetic mutations in the cellular genome triggers an alteration of protein expression, including activation of oncogenes and inactivation of tumor suppressor genes, leading a lack of control in the cell cycle and an uncontrolled proliferation as well as apoptosis evasion. The disease progression continues when exists a failure in the immune system and a tumor forms. Vascularization, invasion of adjacent tissues and metastasis then occur.
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