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Cannabidiol (CBD) Anxiolytic Mechanism in Hippocampus
Description
This template shows how CBD inhibits fatty acid amide hydrolase to increase anandamide signaling through CB1/2 receptors, activating PI3K/Akt and Raf/MEK/ERK pathways that converge on CREB phosphorylation. This drives gene expression of BDNF, synapsin-1, calbindin, and other factors linked to hippocampal neuron proliferation, differentiation, and survival.
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