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Canonical and Non-Canonical NFkB signalling

Molly McKenzie
3+
Creator
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An editable high resolution scientific image depicting Canonical and Non-Canonical NFkB signalling

Description

An illustration of the differences between canonical NFkB signalling and non-canonical NFkB signalling; it has been recognised that these two pathways play an important role in inflammation and diseases such as cancer. The canonical pathway is rapid and transient, associated with acute inflammation. The non-canonical pathway activation results in slower and sustained inflammatory signalling, associated with systemic inflammation.
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