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BioRender Template
CAR-Engrafted T cell and Tumor Cell
Description
This template shows a CAR-engrafted T cell recognizing a tumor-associated antigen on a tumor cell through its chimeric antigen receptor, alongside the T cell's native TCR that recognizes MHC I. Antigen engagement triggers intracellular signaling and release of granzymes, perforin, IL-2, IFN-gamma, and TNF-alpha, as well as FASL and TRAIL death receptor ligands, driving apoptosis of the tumor cell.
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