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BioRender Template
Cas protein variants and engineered tools derived from the CRISPR-Cas family
Creator
s
Description
This figure showcases diverse CRISPR-Cas tools for genome and transcriptome editing. At the center, the Cas9-sgRNA complex forms the basis for modifications. Highlighted are base and prime editors enabling precise edits without DSBs, high-fidelity Cas9 for reduced off-target effects, transcriptional modulators (CRISPRa/i), PAM-expanded variants (SpRY, SpCas9-NG), and natural Cas variants (Cas12, Cas13, Cas14). These tools offer versatility for genetic and epigenetic applications.
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