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CD4⁺ T Cell Fate: From Naive to Memory Across Antigen Encounters
Creator
s
Description
Panel A: Primary Response
Innate immunity (orange) activates rapidly. CD4⁺ T cells (Th, green) coordinate the adaptive response; most die, but some form long-lived memory T cells (blue).
Panel B: Secondary Response
Innate response is similar. Memory CD4⁺ T cells respond more rapidly and robustly, boosting Th cell expansion and function.
Key Insight:
Memory T cells drive faster, stronger responses—forming the basis of effective vaccination.
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