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Cellular processing of shRNAs and sources of by-products

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Xavier Bofill de ros

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Description: This schematic illustrates the alternative processing of pri-shRNAs by DROSHA, where cleavage site variations affect downstream processing. Similarly, design defects can influence DICER1-mediated cleavage or preferential strand selection, leading to the incorporation of the passenger strand into AGO.

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What does the Cellular processing of shRNAs and sources of by-products template show?

This schematic illustrates the alternative processing of pri-shRNAs by DROSHA, where cleavage site variations affect downstream processing. Similarly, design defects can influence DICER1-mediated cleavage or preferential strand selection, leading to the incorporation of the passenger strand into AGO.

Is the Cellular processing of shRNAs and sources of by-products template free to use?

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Unlock publication permissions with a paid plan, and include 'Created with BioRender.com' in your figure legend, or cite BioRender directly per your journal's guidelines.

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