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Cellular Uptake of MIL-89 Nanoparticles into Endocytic Vesicles

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Dana Al-ansari

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BioRender Team

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Description: This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. Illustration of the proposed mechanism of MIL-89 nanoparticles (nanoMIL-89) cellular uptake and internalization into endocytic vesicles. (i) NanoMIL-89 were taken up by endocytosis, packaged into an endosome, and (ii) fused with a lysosome, forming (iii) an endolysosome vesicle. The reassembly and aggregation of nanoMIL-89 is triggered by the acidic environment within the interior membrane of the lysosome.

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This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. Illustration of the proposed mechanism of MIL-89 nanoparticles (nanoMIL-89) cellular uptake and internalization into endocytic vesicles. (i) NanoMIL-89 were taken up by endocytosis, packaged into an endosome, and (ii) fused with a lysosome, forming (iii) an endolysosome vesicle. The reassembly and aggregation of nanoMIL-89 is triggered by the acidic environment within the interior membrane of the lysosome.

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